(-2147024891, 'Access is denied.', None, None) - python-3.x

Question

I am developing a Django (v 3.2.6) application (Python 3.9.1.) which needs to write into an Excel file using pywin32.com.
On the client side it works fine, but when I put in production using IIS (v 10) on a Windows 11 server, I get the error above.
I have a routine that reads in a file input by the user and writes to the project directory:
if request.method == 'POST':
# Create a form instance and populate it with the file from the request (binding):
form = Name1_uploadForm(request.POST, request.FILES)
if form.is_valid():
# Create variable for uploaded file
uploaded_excel_file = form.cleaned_data['excel_file']
# Write it to BASE_DIR
with open(os.path.join(settings.BASE_DIR, form.cleaned_data['excel_file'].name), 'wb+') as destination:
for chunk in uploaded_excel_file.chunks():
destination.write(chunk)
# Allow the write process to conclude
time.sleep(12)
# Close the file
destination.close()
# Call conversion function
Name1_extraction(os.path.join(settings.BASE_DIR, form.cleaned_data['excel_file'].name))
# redirect to a new URL:
return HttpResponseRedirect(reverse('index') )
else:
form = Name1_uploadForm()
This calls another function (below) that should open that same file:
def Name1_extraction(uploaded_excel_file):
const = win32.constants
# Need to run CoInitialize to use win32com.client
pythoncom.CoInitialize()
# Open Name1 excel with Win32com
excelFile = win32.gencache.EnsureDispatch('Excel.Application')
The complete error is the following:
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The error occurs when the following line of code is executed:
excelFile = win32.gencache.EnsureDispatch('Excel.Application')
The application pool is IIS AppPool\DefaultAppPool.
DefaultAppPool has been granted full access to folders C:\Windows\SysWOW64\config\systemprofile\Desktop and C:\Windows\System32\config\systemprofile\Desktop
With these actions I would not expect to see any errors
Thank you for any help provided.

Answer 1

Microsoft does not recommend or support server-side Automation of Office, and Microsoft strongly recommends that developers look for alternatives to Automation of Office when they need to develop server-side solutions.
Due to limitations in the design of Office, changing the Office configuration alone is not sufficient to resolve all issues. Microsoft strongly recommends some alternatives that don't require a server-side installation of Office and can perform most common tasks more efficiently and faster than Automation.
Most server-side automation tasks involve document creation or editing. Office 2007 supports the new Open XML file format, which allows developers to create, edit, read, and transform file content on the server side. This is the recommended and supported method of handling changes to Office files from the service.
How to use the Open XML SDK 2.5 for Office, please refer to the Microsoft documentation:
https://learn.microsoft.com/en-us/office/open-xml/open-xml-sdk
Considerations for server-side Automation of Office, please refer to this Microsoft blog:
https://support.microsoft.com/en-us/topic/considerations-for-server-side-automation-of-office-48bcfe93-8a89-47f1-0bce-017433ad79e2

Answer 2

I've had a similar problem:
I had a Python program with the xlwings library and I created a .bat file.
When I launched it by hand it worked perfectly, but with Windows 10 Scheduler I received an error "(-2147024891, 'Access denied.', None, None)".
I carried out the automatic correction of the Excel file which can be done by going to Excel > File > Info > Verify document.
My problem was that the Windows Scheduler didn't accept comments in the .xlsm file.
I deleted all the comments and then the Windows Scheduler started