IIS - [Exception: Debugger detected - this software cannot run with Debugger.] - iis

Question

I have some handlers running on the IIS server in Windows server 2019. All this handlers are working fine as expected for all the requests.
Suddenly from yesterday, weirdly server is responding failure for the all the request without any changes on the hosted application. Im not attaching to the debugger or any such debugging tools.
Here is the error:
[Exception: Debugger detected - this software cannot run with
Debugger.] AuthorizeService.RegistryProvider.BuildPartition() +68
.cctor() +8
[TypeInitializationException: The type initializer for ''
threw an exception.]
System.RuntimeTypeHandle.CreateInstance(RuntimeType type, Boolean
publicOnly, Boolean noCheck, Boolean& canBeCached,
RuntimeMethodHandleInternal& ctor, Boolean& bNeedSecurityCheck) +0
System.RuntimeType.CreateInstanceSlow(Boolean publicOnly, Boolean
skipCheckThis, Boolean fillCache, StackCrawlMark& stackMark) +119
System.RuntimeType.CreateInstanceDefaultCtor(Boolean publicOnly,
Boolean skipCheckThis, Boolean fillCache, StackCrawlMark& stackMark)
+232 System.Activator.CreateInstance(Type type, Boolean nonPublic) +83 System.RuntimeType.CreateInstanceImpl(BindingFlags bindingAttr, Binder binder, Object[] args, CultureInfo culture, Object[]
activationAttributes, StackCrawlMark& stackMark) +1088
System.Activator.CreateInstance(Type type, BindingFlags bindingAttr,
Binder binder, Object[] args, CultureInfo culture, Object[]
activationAttributes) +124 System.Activator.CreateInstance(Type
type, BindingFlags bindingAttr, Binder binder, Object[] args,
CultureInfo culture) +20
System.Web.HttpRuntime.CreateNonPublicInstance(Type type, Object[]
args) +60
System.Web.HttpRuntime.CreateNonPublicInstanceByWebObjectActivator(Type
type) +59
System.Web.HttpApplication.BuildIntegratedModuleCollection(List`1
moduleList) +167
System.Web.HttpApplication.GetModuleCollection(IntPtr appContext)
+1068 System.Web.HttpApplication.RegisterEventSubscriptionsWithIIS(IntPtr
appContext, HttpContext context, MethodInfo[] handlers) +82
System.Web.HttpApplication.InitSpecial(HttpApplicationState state,
MethodInfo[] handlers, IntPtr appContext, HttpContext context) +173
System.Web.HttpApplicationFactory.GetSpecialApplicationInstance(IntPtr
appContext, HttpContext context) +218
System.Web.Hosting.PipelineRuntime.InitializeApplication(IntPtr
appContext) +296
[HttpException (0x80004005): The type initializer for '' threw
an exception.] System.Web.HttpRuntime.FirstRequestInit(HttpContext
context) [phone]
System.Web.HttpRuntime.EnsureFirstRequestInit(HttpContext context) +95
System.Web.HttpRuntime.ProcessRequestNotificationPrivate(IIS7WorkerRequest
wr, HttpContext context) +254
Version Information: Microsoft .NET Framework Version:4.0.30319;
ASP.NET Version:4.7.3429.0
I'm suspecting there is some configuration issue on IIS that needs to be modified. On IIS Manager, [.Net Compilation] => [Debug] already set to [false]. Also, [Server side Debug mode] on ASP set to [False].

Answer 1

Did you insert any dl-ls into the References? They might be old and may not work which is causing the program to not work just go to the Debug of the program, %userprofile%\source\repos{NameOfProgram}{NameOfProgram}\Bin\Debug{ProgramFileName}, and it should start the program. Just don't debug it will give an error while inserting the code of the program.
%userprofile% represents current user