Cassandra - Poor Query Performance using NetworkTopologyStrategy - cassandra

Question

Having performance issues using NetworkTopologyStrategy on a production keyspace with replication factor 4 across multiple datacenters (DCs located in 4 worldwide locations). Each DC has 3 nodes with pretty good hardware (70GB RAM, 5TB SSDs, etc.).
Same keyspace performs well in a SimpleStrategy using 4 node cluster in AWS, but running same queries in Production environment results in poor query times (select * from my_table is 6ms in AWS and 271ms in production).
Table "my_table" (name changed for privacy) is defined as:
CREATE TABLE my_table (
rec_type text,
group_id int,
rec_id timeuuid,
user_id int,
content text,
created_on timestamp,
PRIMARY KEY ((rec_type, group_id), rec_id)
) WITH bloom_filter_fp_chance = 0.1
AND comment = ''
AND dclocal_read_repair_chance = 0.1
AND default_time_to_live = 0
AND gc_grace_seconds = 864000
AND max_index_interval = 2048
AND memtable_flush_period_in_ms = 0
AND min_index_interval = 128
AND read_repair_chance = 0.0
AND speculative_retry = '99.0PERCENTILE'
AND caching = {
'keys' : 'ALL',
'rows_per_partition' : 'NONE'
}
AND compression = {
'sstable_compression' : 'LZ4Compressor'
}
AND compaction = {
'class' : 'LeveledCompactionStrategy'
};
This is a newly-created table in Production with occasional updates and low tombstone count.
Query trace is below:
Looks like range requests are taking the most amount of time. What would be the cause of the delay?
Network latency between nodes in the same DC is <1ms and latency between DCs is around 50-60ms.
EDIT:
Below is the query trace for a select * from my_table where rec_type = 'abc' and group = 1 LIMIT 300 query (2 screenshots because trace is so long):